Anti-AFP Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price
ASPC881	Anti-AFP Antibody	Mouse IgG1, Kappa	None	$460	Add
ASPC881-A	Anti-AFP Antibody, APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC881-B	Anti-AFP Antibody, Biotin	Mouse IgG1, Kappa	Biotin	$680	Add
ASPC881-H	Anti-AFP Antibody, HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC881-P	Anti-AFP Antibody, PE	Mouse IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC881

Anti-AFP Antibody

Mouse IgG1, Kappa

None

$460

Add

ASPC881-A

Anti-AFP Antibody, APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC881-B

Anti-AFP Antibody, Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

ASPC881-H

Anti-AFP Antibody, HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC881-P

Anti-AFP Antibody, PE

Mouse IgG1, Kappa

$1,180

Add

Anti-AFP Monoclonal Antibody
- Product Description:
  
  The Anti-AFP antibody is a mouse monoclonal antibody recommended for use in immunohistochemistry, immunofluorescence, enzyme-linked immunosorbent assay and other applications. This antibody specifically targets AFP and demonstrates reactivity with human.
  
  Applications:
  
  Immunohistochemistry, Immunofluorescence, Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  AFP
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human AFP.
  
  Immunogen:
  
  Human AFP.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-AFP Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

AFP

Protein Name

Alpha-fetoprotein

Introduction

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Alternative Names

AFPD; FETA; HPAFP

Gene ID

174

UniProt

P02771

Subcellular Location

Secreted.

Tissue Specificity

Plasma. Synthesized by the fetal liver and yolk sac.

Cell Line Specificity

Cancer enriched

Function

Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.

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