Anti-ADORA2A Monoclonal Antibody (12G12)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC800	Anti-ADORA2A Antibody (12G12)	Mouse IgG2a, Kappa	None	$460	In stock	Add
ASPC800-P	Anti-ADORA2A Antibody (12G12), PE	Mouse IgG2a, Kappa	PE	$1,180	2-3 weeks	Add
ASPC800-A	Anti-ADORA2A Antibody (12G12), APC	Mouse IgG2a, Kappa	APC	$980	2-3 weeks	Add
ASPC800-H	Anti-ADORA2A Antibody (12G12), HRP	Mouse IgG2a, Kappa	HRP	$600	2-3 weeks	Add
ASPC800-B	Anti-ADORA2A Antibody (12G12), Biotin	Mouse IgG2a, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC800

Anti-ADORA2A Antibody (12G12)

Mouse IgG2a, Kappa

None

$460

In stock

Add

ASPC800-P

Anti-ADORA2A Antibody (12G12), PE

Mouse IgG2a, Kappa

$1,180

2-3 weeks

Add

ASPC800-A

Anti-ADORA2A Antibody (12G12), APC

Mouse IgG2a, Kappa

APC

$980

2-3 weeks

Add

ASPC800-H

Anti-ADORA2A Antibody (12G12), HRP

Mouse IgG2a, Kappa

HRP

$600

2-3 weeks

Add

ASPC800-B

Anti-ADORA2A Antibody (12G12), Biotin

Mouse IgG2a, Kappa

Biotin

$680

2-3 weeks

Add

Anti-ADORA2A Monoclonal Antibody (12G12)
- Product Description:
  
  The Anti-ADORA2A antibody is a mouse monoclonal antibody recommended for use in ELISA and other applications. This antibody specifically targets ADORA2A and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  ADORA2A
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human ADORA2A.
  
  Immunogen:
  
  Human ADORA2A protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  12G12
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ADORA2A Monoclonal Antibody (12G12) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ADORA2A

Protein Name

Adenosine receptor A2a

Introduction

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]

Alternative Names

ADORA2A; adenosine A2a receptor; A2aR; RDC8; ADORA2; adenosine receptor A2a; adenosine receptor subtype A2a

Gene ID

135

UniProt

P29274

Subcellular Location

Cell membrane

Cell Line Specificity

Cancer enhanced

Function

Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).