Anti-ACVR2B Monoclonal Antibody (15F8)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC665	Anti-ACVR2B Antibody (15F8)	Human IgG4, Kappa	None	$460	In stock	Add
ASPC665-P	Anti-ACVR2B Antibody (15F8), PE	Human IgG4, Kappa	PE	$1,180	2-3 weeks	Add
ASPC665-A	Anti-ACVR2B Antibody (15F8), APC	Human IgG4, Kappa	APC	$980	2-3 weeks	Add
ASPC665-H	Anti-ACVR2B Antibody (15F8), HRP	Human IgG4, Kappa	HRP	$600	2-3 weeks	Add
ASPC665-B	Anti-ACVR2B Antibody (15F8), Biotin	Human IgG4, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC665

Anti-ACVR2B Antibody (15F8)

Human IgG4, Kappa

None

$460

In stock

Add

ASPC665-P

Anti-ACVR2B Antibody (15F8), PE

Human IgG4, Kappa

$1,180

2-3 weeks

Add

ASPC665-A

Anti-ACVR2B Antibody (15F8), APC

Human IgG4, Kappa

APC

$980

2-3 weeks

Add

ASPC665-H

Anti-ACVR2B Antibody (15F8), HRP

Human IgG4, Kappa

HRP

$600

2-3 weeks

Add

ASPC665-B

Anti-ACVR2B Antibody (15F8), Biotin

Human IgG4, Kappa

Biotin

$680

2-3 weeks

Add

Anti-ACVR2B Monoclonal Antibody (15F8)
- Product Description:
  
  The Anti-ACVR2B antibody is a human monoclonal antibody recommended for use in flow cytometry and other applications. This antibody specifically targets ACVR2B and demonstrates reactivity with human.
  
  Applications:
  
  Flow Cytometry
  
  Target:
  
  ACVR2B
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human ACVR2B.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  15F8
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ACVR2B Monoclonal Antibody (15F8) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ACVR2B

Protein Name

Activin receptor type-2B

Introduction

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

Alternative Names

Activin A Receptor Type 2B; Activin A Receptor, Type IIB; EC 2.7.11.30; ActR-IIB; Activin Receptor Type IIB; Activin Receptor Type-2B; EC 2.7.11; ACTRIIB; HTX4

Gene ID

UniProt

Q13705

Related Disease

Heterotaxy, visceral, 4, autosomal (HTX4)

Subcellular Location

Cell membrane

Cell Line Specificity

Cancer enhanced

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