Anti-ACVR1 Monoclonal Antibody (12F2)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC507	Anti-ACVR1 Antibody (12F2)	Rat IgG1, Kappa	None	$460	In stock	Add
ASPC507-P	Anti-ACVR1 Antibody (12F2), PE	Rat IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC507-A	Anti-ACVR1 Antibody (12F2), APC	Rat IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC507-H	Anti-ACVR1 Antibody (12F2), HRP	Rat IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC507-B	Anti-ACVR1 Antibody (12F2), Biotin	Rat IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC507

Anti-ACVR1 Antibody (12F2)

Rat IgG1, Kappa

None

$460

In stock

Add

ASPC507-P

Anti-ACVR1 Antibody (12F2), PE

Rat IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC507-A

Anti-ACVR1 Antibody (12F2), APC

Rat IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC507-H

Anti-ACVR1 Antibody (12F2), HRP

Rat IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC507-B

Anti-ACVR1 Antibody (12F2), Biotin

Rat IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-ACVR1 Monoclonal Antibody (12F2)
- Product Description:
  
  The Anti-ACVR1 antibody is a rat monoclonal antibody recommended for use in ELISA, flow cytometry and other applications. This antibody specifically targets ACVR1 and demonstrates reactivity with human and mouse.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Flow Cytometry
  
  Target:
  
  ACVR1
  
  Target Species:
  
  Mouse
  
  Specificity:
  
  This antibody reacts with Mouse Acvr1.
  
  Immunogen:
  
  Recombinant Mouse ACVR1 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  12F2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ACVR1 Monoclonal Antibody (12F2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ACVR1

Protein Name

Activin receptor type-1

Introduction

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Alternative Names

ALK2; Acvr; Alk8; SKR1; Alk-2; Tsk7L; ActR-I; ActRIA; Acvrlk2; D330013D15Rik

Gene ID

11477

UniProt

P37172

Subcellular Location

Membrane; Single-pass type I membrane protein.

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