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OCT4 Purified Protein

OCT4 Purified Protein

Catalog Number:

CRT1277979APP

Mfr. No.:

APPL_000009P

Price:

$1,463

Size:

50 μg

Quantity:

Add to Cart:

- Overview
  - Please contact us at for specific academic pricing.
    
    More Details
    
    iPSC Generation
- Properties
  - Categories
    
    iPSC Reprogramming
    
    Concentration
    
    250ug/ml
    
    Other Properties
    
    Species: Human (H. sapiens)
    
    Storage
    
    PBS
    
    Shipping
    
    On dry ice.
    
    * For research use only. Not for diagnostic or therapeutic use.
- Applications
  - Application Description
    
    Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). OCT4 forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. OCT4 is critical for early embryogenesis and for embryonic stem cell pluripotency. OCT4 is one of the four factors in both the Thomson and the Yamanaka protocol for iPSC reprogramming. The recombinant protein within the lysate has a 6X His tag at N-terminus for purification and 9X Arginine at C-terminus for cell membrane penetration.
- Reference
  - Kirita, K et al. "Identification of Biological Properties of Intralymphatic Tumor Related to the Development of Lymph Node Metastasis in Lung Adenocarcinoma" PloS One 12:e83537 (2013). DOI: 10.1371/journal.pone.0083537.

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