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KLF4 Purified Protein

KLF4 Purified Protein

Catalog Number:

CRT1277943APP

Mfr. No.:

APPL_000001P

Price:

$1,463

Size:

50 μg

Quantity:

Add to Cart:

- Overview
  - Please contact us at for specific academic pricing.
    
    More Details
    
    iPSC Generation
- Properties
  - Categories
    
    iPSC Reprogramming
    
    Concentration
    
    250ug/ml
    
    Other Properties
    
    Species: Human (H. sapiens)
    
    Storage
    
    PBS
    
    Shipping
    
    On dry ice.
    
    * For research use only. Not for diagnostic or therapeutic use.
- Applications
  - Application Description
    
    Transcription factor which acts as both an activator and repressor. KLF4 binds the CACCC core sequence. It also binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. KLF4 is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. KLF4 is one of the four factors in the Yamanaka protocol for iPSC reprogramming. The purified recombinant protein has a 6X His tag at N-terminus for purification and 9X poly-arginine at C-terminus for cell membrane penetration.

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