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Overview
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Predicted MW: Monomer, 7.9 kDa (73 aa). Growth regulated protein alpha (GRO-alpha), also known as CXCL1, is a chemokine that has mitogenic properties and is a neutrophil chemoattractant. GRO-alpha is secreted by macrophages, epithelial cells, neutrophils, and melanomas. GRO-alpha signals through the CXCR2 chemokine receptor and is important during spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing.
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Overview