Chlorpromazine

Chlorpromazine

Catalog Number:
L002373290APE
Mfr. No.:
APE-C6410
Price:
$188
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      • Overview
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          Background

          Chlorpromazine is a member of the typical antipsychotic or neuroleptic drug class (also known as first-generation antipsychotics), used to manage and treat schizophrenia, bipolar disorder, as well as acute psychosis. Chlorpromazine exerts its antipsychotic effect by the post-synaptic blockade at the dopamine D2 receptors in the mesolimbic pathway. Also, chlorpromazine exhibits antiemetic effect by the combined blockade at dopamine D2, histamine H1, and muscarinic M1 receptors in the vomiting center, extending its indications for alleviation of nausea and vomiting. Chlorpromazine is commonly present as the hydrochloride salt in oral and injectable forms, and as the base in the suppositories.

      • Properties
        • Categories
          A dopamine receptor antagonist, classified as a typical antipsychotic drug
          Alternative Name
          3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
          CAS Number
          50-53-3
          Molecular Formula
          C17H19ClN2S
          Molecular Weight
          318.86
          Purity
          98%
          Solubility
          ≥64mg/mL in DMSO
          Storage
          Store at -20°C
          SMILES
          ClC1=CC(N2CCCN(C)C)=C(C=C1)SC3=C2C=CC=C3

          * For Research Use Only

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