CacoGoblet 24 Transwell (Custom setup)

Ready-to-use cell-based in vitro 24 individual transwell plate cocultured with Caco-2 and human goblet cells (HT-29).
Main Indication Description: In vitro intestinal absorption evaluation of tested compounds in a cell-based barrier physiologically similar to the intestinal epithelium.

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Background

CacoGoblet, a secreting mucus intestinal barrier
24 transwell insert plates seeded with 21 days differentiated and polarized Caco-2 and HT-29 cells with an absorptive and mucus-secreting phenotype, respectively. This co-culture model enables the evaluation of anti-inflammatory drug efficacy by assessing cellular responses to inflammatory mediators. Additionally, its physiologically relevant barrier allows for studying in intestinal absorption of drug candidates.

We recommend acquiring this product together with the CacoGoblet Cell Culture Medium to ensure optimal performance and reproducibility.