Anti-EGFR antibody

Catalog Number:
STJ180089
Price:
$699
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      • Overview
        • EGFR is type I receptor tyrosine kinase with sequence homology to erbB‐1, ‐2, ‐3 ‐4 or HER‐1, ‐2, ‐3 ‐4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor‐ a (TGFa), Heparin‐binding EGF (HB‐EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

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      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human
          Clone
          EP22
          Immunogen
          A synthetic phospho‐peptide corresponding to residues surrounding Tyr1068 of human EGF receptor
          Conjugate
          Unconjugated
          Formulation
          Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
          Storage
          Store at 2-8°C for up to 1 year
          Regulatory Status
          RUO
          Antigen
          Epidermal Growth Factor Receptor; Proto-Oncogene C-Erbb-1; Receptor Tyrosine-Protein Kinase Erbb-1 (Gene ID:1956; UniProt:P00533)

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC (paraffin) 1:50‐100
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