Anti-CTNNB1 antibody

Catalog Number:
STJ180013
Price:
$642
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      • Overview
        • Beta‐catenin is a 92 kD protein normally found in the cytoplasm of the cell in the submembranouslocation. This protein is associated with E‐cadherin and may be essential for the function of E‐cadherin. Mutations in the Beta‐catenin gene result in loss of membranous staining and nuclear accumulation of this protein. Nuclear accumulation of this protein has been demonstrated in desmoid‐type fibromatosis lesions of the breast and abdomen and therefore is useful in differentiating this lesion from other spindle cell lesions that may occur in these locations. Nuclear accumulation of Beta‐ catenin has also been demonstrated in colorectal carcinom

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      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human
          Clone
          EP35
          Immunogen
          A synthetic peptide corresponding to residues near N‐terminus of human β‐catenin
          Conjugate
          Unconjugated
          Formulation
          Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
          Storage
          Store at 2-8°C for up to 1 year
          Regulatory Status
          RUO

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC (paraffin) 1:50‐100
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